Development of Spray Made From Kelakai Leaves (Stenochlaena palustris) and Effectiveness in the Healing of Perineal Wounds

Authors

  • Ida Ayu Oktari Applied Master Program Midwifery Study Program, Poltekkes Kemenkes Semarang, Semarang, Central Java, Indonesia
  • Krisdiana Wijayanti Poltekkes Kemenkes Semarang, Semarang, Central Java, Indonesia
  • M. Choiroel Anwar Poltekkes Kemenkes Semarang, Semarang, Central Java, Indonesia

DOI:

https://doi.org/10.31965/infokes.Vol23.Iss3.1919

Keywords:

Kelakai, Spray, Perineal Wound, Irritation Test

Abstract

The prognosis or possible diagnosis in postpartum mothers with perineal suture wounds is the possibility of infection of perenium suture wounds. Kelakai leaf plants are plants that contain flavonoids, tannins, saponins, alkaloids, and tripenoids. This study aims to innovate and develop perineal wound medicine using kelakai leaf spray and analyze its effectiveness based on REEDA scale indicators (redness,edema, ecchymosis, discharge, approximation). This study uses a quantitative method with a Reseach and development approach. The sampling technique uses non-probability sampling with a type of purposive sampling selecting 34 respondents, who are divided directly between the two groups. The intervention group received treatment of perineal wounds for 7 days with kelakai leaf spray and education on how to treat perineal wounds, while the control group received treatment with placebo spray and education on how to treat perineal wounds. The spray is administered four times a day with a dose of four sprays. Wound healing was measured by the REEDA Scale on days 3, 5, and 7. A tool to measure hb levels with digital hb, to measure protein intake, calorie intake, and fe intake using food recall. Data analysis includes Friedman and Mann Whitney as well as Stratification. The results showed that there was a difference in the average healing of perineal wounds at the observation time between the intervention group and the control group (p=0.000). On average, the difference in perineal wound healing using the REEDA scale showed a significant difference between the intervention group and the control group (p=0.000). A value of 3.2 is considered a relatively large measure of effect. The irritation test obtained results that did not cause irritation, In conclusion, the developed Kelakai leaf spray was effective in helping to accelerate the healing of perineal wounds, as evidenced by the difference in the mean healing time of perineal wounds with the SIGINFIC REEDA scale in postpartum mothers in the intervention group compared to the control group (p=0.000).

Downloads

Download data is not yet available.

References

Akhmadi, C., & Utami, W. (2022). Senyawa Fitokimia dan Aktivitas Farmakologi Family Basellaceae sebagai Obat Luka: A Narrative Review. Generics: Journal of Research in Pharmacy, 2(2), 77-85. https://doi.org/10.14710/genres.v2i2.13798

Alim, Z. (2021). Penatalaksanaan Luka Perineum Pada Ibu Nifas. Malang: Literasi Nusantara Abadi.

Astuti, R. A., Irwandi, I., & Muslihin, A. M. (2022). Uji Efektivitas Ekstrak Etanol Lidah Buaya Terhadap Penyembuhan Luka Full Thickness. Jurnal Etnofarmasi, 1(02), 1-4. https://doi.org/10.36232/jurnalfarmasiunimuda.v1i02.1730

Badan Pengawas Obat dan Makanan Indonesia. (2022). Peraturan Badan Pengawas Obat dan Makanan Nomor 10 Tahun 2022 tentang Pedoman Uji Toksisitas Praklinik secara in Vivo. Badan Pengawas Obat dan Makanan Indonesia.

Chairperson of The Indonesian Food and Drug Authority. (2022). Regulation of The Indonesian Food and Drug Authority Number 26 of 2022 on Importation Control of Food and Drug Substances Into The Territory of Indonesia. Jakarta:

Chairperson of The Indonesian Food and Drug Authority.

Dona, S., Afriyanti, S., & Rahmawati, D. (2023). Identifikasi Penyembuhan Luka Perineum Menggunakan Skala Reeda Pada Ibu Yang Diberikan Teh Kalakai. Dinamika Kesehatan: Jurnal Kebidanan Dan Keperawatan, 14(2), 310–319. https://doi.org/10.33859/dksm.v15i1.936

Sugiyono, S. (2020). Metode Penelitian Kuantitatif Kualitatif dan R&D. Bandung: CV. Alfabeta, Bandung.

Fadhila, D. F. D., Hamidah, S., & Istikowati, W. T. (2023). Kerapatan Stomata, Warna dan Kadar Klorofil Daun Kelakai (Stenochlaena palustris (Burm. F) Beddome) berdasarkan Perbedaan Lokasi Tumbuh dan Tingkat Umur Daun. Journal of Forest Science Avicennia, 6(1), 78-84. Retrieved from: https://ejournal.umm.ac.id/index.php/avicennia/article/view/21860

Fajri, I., Nurhamsyah, D., Aisyah, S., Mudrikah, K. A., & Azjurnia, A. R. (2022). Terapi non-farmakologi dalam mengurangi tingkat nyeri pada pasien kanker payudara stadium 2-4: literature review. Jurnal Ilmiah Keperawatan Indonesia (JIKI), 5(2), 106-120. https://doi.org/10.31000/jiki.v5i2.6139

Faridi, A., Trisutrisno, I., Irawan, A. M. A., Lusiana, S. A., Alfiah, E., Rahmawati, L. A., ... & Sinaga, T. R. (2022). Survei Konsumsi Gizi. Yayasan Kita Menulis.

Festy, P., Wulandari, Y., & Syawaliyah, M. (2021, January). The Relationship of Nutritional Status and Perineal Wound Healing Among Post-Partum Women. In 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020), pp. 500-503. https://doi.org/10.2991/ahsr.k.210115.098

Girsang, B. M. (2021). Buku Ajar Aplikasi Periode Postpartum. Insan Cendekia. Sumatera Barat.

Grada, A., & Phillips, T. J. (2022). Nutrition and cutaneous wound healing. Clinics in Dermatology, 40(2), 103–113. https://doi.org/10.1016/j.clindermatol.2021.10.002

Hakim, A. R., Savitri, A. S., & Saputri, R. (2021). A Aktivitas Antioksidan Dari Infusa Kelakai (Stenochlaena palustris (Burm. F) Bedd). Journal Pharmaceutical Care and Sciences, 1(2), 121-125. https://doi.org/10.33859/jpcs.v2i1.69

Hanifa, D., Hadisaputro, S., Supriyana, S., & Santoso, B. (2020). Purple Yam Extract (Dioscorea Alata L.) As Adjuvant Antihipertension Medicine for Postpartum Hipertension. STRADA: Jurnal Ilmiah Kesehatan, 9(2), 443-449. https://doi.org/10.30994/sjik.v9i2.363

Hopipah, I. (2024). Hubungan Kadar Haemoglobin, Asupan Protein dan Mobilisasi Dini dengan Penyembuhan Luka Perineum pada Ibu Nifas. Indonesia Journal of Midwifery Sciences, 3(3), 466–474. https://doi.org/10.53801/ijms.v3i3.180

Jamilah, J., Billi, J., & Effendi, H. (2022). Pengaruh pemberian sediaan salep ekstrak daun dan batang kelakai (Stenochlaena palustris (Burm. f) Bedd) terhadap penyembuhan luka sayat pada kulit tikus putih. Jurnal Kesehatan Borneo Cendekia, 6(1), 76-87. https://doi.org/10.54411/Jbc.V6i1.278

Karimah, N., Khafidhoh, N., & Hardjanti, T. S. (2022). Daun Sirih Merah Ampuh Menyembuhkan Luka Perineum Pada Ibu Nifas. Poltekkes Kemenkes Semarang. Semarang.

Kasmiati, K. (2023). Asuhan Kebidanan Masa Nifas. Malang: CV. Literasi Nusantara Abadi.

Kusuma, A. B. C., Limanan, D., Yulianti, E., & Ferdinal, F. (2024). Uji Kapasitas Antiokisdan pada Ekstrak Daun Peppermint (Mentha piperita L.) dengan Metode DPPH, FRAP, ABTS. Jurnal Sehat Indonesia (JUSINDO), 6(02), 878–886. https://doi.org/10.59141/jsi.v6i02.155

Maesaroh, I., & Fahmilik, L. (2021). Formulasi dan evaluasi sediaan spray gel ekstrak bunga marigold (Tagetes Erecta L) sebagai antioksidan. Jurnal Komunitas Farmasi Nasional, 1(1), 26–37. Retrieved from: https://jkfn.akfaryarsiptk.ac.id/index.php/jkfn/article/view/6/3

Ministry of Health of the Republic of Indonesia. (2021). Indonesia Health Profile 2021. Jakarta: Indonesian Ministry of Health.

Nurjaya, W. A. & Bahja, B. (2023). Buku Ajar Ilmu teknologi Pangan. Palu: Jurusan Gizi Poltekkes Kemenkes Palu.

Oksal, E., Ayuchecaria, N., Agnestisia, R., Ariska, R., Tampubolon, M. J. L., Dewi, S. A., Maulana, I., & Rizkita, A. D. (2023). Review Article: Antioxidant Activity In Kalakai (Stenochlaena palustris). ALOTROP, 7(2), 1–9. https://doi.org/10.33369/alo.v7i2.29209

Putria, D. K., Salsabila, I., Darmawan, S. A. N., Pratiwi, & Nihan, Y. A. (2022). Identifikasi Tanin pada Tumbuh-tumbuhan di Indonesia. PharmaCine : Journal of Pharmacy, Medical and Health Science, 3(1), 11–24. https://doi.org/10.35706/pc.v3i1.7238

Resmanisih, K., & Rusmini, R. (2023). Pengaruh Posisi Bersalin Setengah Duduk Terhadap Ruptur Perineum Pada Primigravida Di Wilayah Kerja Puskesmas Pahandut. IMJ (Indonesian Midwifery Journal), 4(1), 28-33. http://dx.doi.org/10.31000/imj.v4i1.3913

Rostika, T., Choirunissa, R., & Rifiana, A. J. (2020). Pemberian Penggunaan Air Rebusan Daun Sirih Merah Terhadap Waktu Penyembuhan Luka Perineum Derajat I Dan II di Klinik Aster Kabupaten Karawang. Jurnal Ilmiah Kesehatan, 12(2), 196-204. https://doi.org/10.37012/jik.v12i2.269

Saputri, R., Hakim, A. R., Savitri, A. S., Ujuldah, A., Damayanti, A., & Pitriya, A. (2023). Efektivitas Antiinflamasi Ekstrak Etanol Daun Kelakai (Stenochlaena palustris) Asal Gambut Kalimantan Selatan. Sains Medisina, 1(4), 191-194. https://doi.org/10.51817/bjp.v1i1.53

Sikumbang, I. M., Astuti, R. A., Wahyuningtyas, E. S., Lutfiyati, H., Wijayatri, R., & Nasruddin, N. (2020). Wound healing activity of aloe vera extract spray on acute wound in male balb/c mice. Pharmaciana, 10(3), 315. https://doi.org/10.12928/pharmaciana.v10i3.16640

Sindi, F., Wijayanti, K., & Ningtyas, E. A. E. (2024). Pengaruh Spray Gel Ekstrak Batang Bajakah Tampala (Spatholobus Littoralis Hassk) Terhadap Penyembuhan Luka Perineum Pada Ibu Nifas. Media Penelitian dan Pengembangan Kesehatan, 34(3), 571-584. https://doi.org/10.34011/jmp2k.v34i3.2106

Zhao, H., Ren, S., Yang, H., Tang, S., Guo, C., Liu, M., ... & Xu, H. (2022). Peppermint essential oil: Its phytochemistry, biological activity, pharmacological effect and application. Biomedicine & pharmacotherapy, 154, 113559. https://doi.org/10.1016/j.biopha.2022.113559

Downloads

Published

2025-09-22

How to Cite

Oktari, I. A., Wijayanti, K., & Anwar, M. C. (2025). Development of Spray Made From Kelakai Leaves (Stenochlaena palustris) and Effectiveness in the Healing of Perineal Wounds. JURNAL INFO KESEHATAN, 23(3), 494–506. https://doi.org/10.31965/infokes.Vol23.Iss3.1919

Issue

Section

Original Articles

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.